Dr. Tom N. Grossmann

Professor of Organic Chemistry

VU University Amsterdam
Dept. of Chemistry & Pharmaceutical Sci.
De Boelelaan 1108
1081 HZ Amsterdam
The Netherlands

Chemical Genomics Centre (CGC)
of the Max Planck Society
Otto-Hahn-Str. 15
44227 Dortmund
Germany

Email: t.n.grossmann@vu.nl

ResearcherID: A-4175-2015

Curriculum Vitae

Adrian successfully defended his PhD thesis

Congratulations to Adrian Glas

By grossmannlab on Sep 22, 2016

Adrian successfully defended his PhD thesis “Kohlenwasserstoff­verbrückte Peptide mit irregulärer Sekundärstruktur für die Inhibition von Protein-Protein-Interaktionen”.

Constraining an irregular peptide secondary structure via ring-closing alkyne metathesis

Communication in ChemBioChem is online

By grossmannlab on Sep 6, 2016

“Constraining an irregular peptide secondary structure through ring-closing alkyne metathesis”

PM Cromm, K Wallraven, A Glas, D Bier, A Fürstner, C Ottmann, TN Grossmann*, DOI: 10.1002/cbic.201600362

Technische Universität Dortmund

Congratulations to Philipp Cromm

By grossmannlab on Jun 28, 2016

Philipp successfully defended his PhD thesis “Design und Synthese Peptid-basierter Inhibitoren für Protein-Protein-Interaktionen”.

Inside Cover: Angew. Chem. Int. Ed. Volume 55, Issue 36 (2016)

Communication in Angewandte Chemie is online

By grossmannlab on Jun 28, 2016

Congratulations to the Etzkorn lab and thanks for having us onboard. This communication is featured on the inside cover.

“Selective protein hyperpolarization in cell lysates using targeted dynamic nuclear polarization”

T Viennet, A Viegas, A Kuepper, S Arens, V Gelev, O Petrov, TN Grossmann, H Heise, M Etzkorn*, DOI: 10.1002/anie.201603205

Cover: ACS Chem. Biol. Volume 11, Number 8 (2016)

Article in ACS Chemical Biology is online

By grossmannlab on Jun 23, 2016

This article is featured on the cover.

“Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase”

PM Cromm, J Spiegel, P Küchler, L Dietrich, J Kriegesmann, M Wendt, RS Goody, H Waldmann*, TN Grossmann*, DOI: 10.1021/acschembio.6b00386

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

Communication in Nature Communications is online

By grossmannlab on Apr 14, 2016

“Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides”

PM Cromm, S Schaubach, J Spiegel, A Fürstner*, TN Grossmann*, H Waldmann*, DOI: 10.1038/ncomms11300

European Research Council

ERC starting grant projects have been started

By grossmannlab on Mar 5, 2016

“Peptide-derived bioavailable macrocycles as inhibitors of protein-RNA and protein-protein interactions”

Technische Universität Dortmund

Congratulations to Jochen Spiegel and Chang‑Uk Lee

By grossmannlab on Mar 4, 2016

Jochen successfully defended his PhD thesis “Synthese und Evaluierung stabilisierter Bindungsepitope zur Adressierung kleiner GTPasen”.

Chang‑Uk successfully defended his PhD thesis “Structural basis for reversible, oxidative inhibition of PTEN phosphatase activity”.

Lab moves to VU

Lab moves to the VU University Amsterdam

By grossmannlab on Feb 25, 2016

We just moved into the new labs. Personnel and equipment arrived savely.